Coordinator.exe No Disk Drive solution marked my Program Files (x86) for deletion.

I had the problem with Coordinator.exe pop up saying that no disk was in the drive. I came across your March 12, 2012 solution to that problem (problem now closed) and followed Cheeseball81's instructions to download and run Combofix.exe. However, after completing the scan, none of my programs will work. I get a message, "C:/Program files (x86)\(Program file) Illegal Opertion attempted on a registry key that has been marked for deletion."

I'm using Windows 7. Thanks for any help here.